Topical Application

Lipoid’s broad product portfolio contains specialty lecithins and phospholipids for pharmaceutical dermal applications. A broad variety of components and delivery systems with unique properties allows the formulation developer to select the most suited product for a particular drug delivery system such as liposomal dispersions and emulsions.

Topical Application

Our Products
  • Lecithin and Phospholipids
  • Hydrogenated Phospholipids
  • Lysolecithin and –phospholipids
  • Hydrogenated Lysolecithin
  • Liquid Compounds
  • Delivery Systems
Our Brands
  • PhytoSolve®
  • LIPOID Liposome®


Further Information

The main purpose of our largest organ, the skin, is to form a barrier. The surface of the skin protects the body from dehydration and inhibits microorganisms from penetrating the body. The stratum corneum (SC) with its special lipids and corneocytes exhibits the main barrier function of the skin. This barrier hinders the dermal and transdermal application of active ingredients. Only lipophilic molecules with a molecular weight below 500 Da can penetrate intact and healthy skin. In addition the transdermal administration of pharmaceutical actives is influenced by various factors such as age of the patient, skin condition, site of application and skin metabolism. Suitable excipients and delivery systems provide solutions to these problems. Especially phospholipids (PL) offer solutions to these challenges because they:

  • act as transport vehicles (e.g. liposomes, elastic liposomes) and thus can pass the skin barrier
  • fluidize the lipid layer of the SC (unsaturated PL) and therefore increase the permeability
  • increase the skin humidity resulting in swelling of the SC which is accompanied by an increase of the permeability
  • fluidize the lipid layer of the SC (unsaturated PL) and therefore increase the permeability
  • increase the solubility of the active and thus increase the absorption and the bioavailability of the active
  • account for the formation of an active depot in the skin resulting in a slow and steady release of the active
  • protect the active from photo-induced and oxidative degradation